Power 50: Lana & Lilly Wachowski

Photo: Barry Brecheisen/Invision/AP

Lilly Wachowski announced her "sex change shocker" in a humorous statement to the Windy City Times in March, introducing the Wachowski sisters to the world. Her sibling, Lana, came out as trans in 2012. Although the Wachowskis are best known for The Matrix franchise, their recent work includes the big-budget movies Cloud Atlas and Jupiter Ascending. They're currently in production on the second season of their Netflix original series, Sense8, co-starring trans actress and activist Jamie Clayton.